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Selected publications 

2021

• Quantitative mapping of human hair graying and reversal in relation to life stress
  Rosenberg A, Rausser S, Ren J, Mosharov EV, Sturm G, Ogden RT, Patel P, Soni RK, Lacefield C, Tobin DJ, Paus R, Picard M. 
  eLife 2021;10:e67437   PubMed   PDF​   eLife Digest
  
  
• 3D neuronal mitochondrial morphology in axons, dendrites, and cell bodies of the aging mouse hippocampus.
  Faitg J, Lacefied C, Davey T, White K, Laws R, Kosmidi S, Reeve AK, Kandel E, Vincent AE, Picard M. Cell Rep 2021; 36(6): 109509 PubMed   PDF
  
  
• Stress and circulating cell-free mitochondrial DNA: a systematic review of human studies, physiological considerations, and technical recommendations.
  Trumpff C, Michelson J, Lagranha CJ, Taleon V, Karan K, Sturm G, Lindqvist D, Fernström J, Moser D, Kaufman BA, Picard M.
  Mitochondrion 59:225-245   PubMed   PDF​   Protocol
  
  
• Mitochondria in epithelial ovarian carcinoma exhibit abnormal phenotypes and blunted associations with biobehavioral factors
  Bindra S, McGill MA, Triplett MK, Tyagi A, Thaker PH, Dahmoush L, Goodheart MJ, Ogden RT, E Owusu-Ansah, Karan KR, Cole S, Sood AK, Lutgendorf SK, Picard M. Sci Rep 2021; 11:11595   PubMed   PDF​
  
  
• Blood mtDNA copy number: What are we counting?
  Picard M. Mitochondrion 2021 (in press)   PubMed   PDF​
  
  
• The social nature of mitochondria: Implications for human health
  Picard M, Sandi C. Neurosci Biobehav Rev 2021; 120(5):595-610   PubMed   PDF​

2020

• Mitochondrial respiratory chain function modulates LPS-induced inflammatory signatures in human blood
  Karan KR, Trumpff C, McGill MA, Thomas  JE, Sturm G, Lauriola V, Sloan RP, Rohleder N, Kaufman BK, Marsland AL, Picard M. 
  Brain Behav Immun-Health 2020; 100080   PubMed   PDF​   Suppl

​2019

• Mitochondrial psychobiology: Foundation and applications
  Picard M, Trumpff C, Burelle Y. Curr Opin Behav Sci 2020;   PDF
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• Human aging DNA methylation signatures are conserved but accelerated in cultured fibroblasts
  Sturm G, Cardenas A, Bind MA, Horvath S, Wang S, Wang Y, Hägg S, Hirano M, Picard M. Epigenetics 201914(10):961-976   PubMed   PDF
  
  
• Predictors of ccf-mtDNA reactivity to acute psychological stress identified using machine learning classifiers: A proof-of-concept
  Trumpff C, Marsland AL, Sloan RP, Kaufman BK, Picard M. Psychoneuroendocrinol 2019; 107:82-92   PubMed   PDF
  
  
• Acute psychological stress increases serum circulating cell-free mitochondrial DNA
  Trumpff C, Marsland AL, Basualto C, Martin JL, Carroll JE, Sturm G, Gu Z, Vincent A, Kaufman BA, Picard M. Psychoneuroendocrinol 2019; 106:268-276     PubMed   PDF
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• Accelerating research on biological aging and mental health: Current challenges and future directions
  Han LKM, Verhoeven JE, Tyrka A, Penninx BWJH, Wolkowitz OM, Månsson KNT, Lindqvist D, Vinkers CH, Boks MP, Révész D, Mellon SH, Picard M. Psychoneuroendocrinol 2019; 106:293-311   PubMed   PDF
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• Quantitative 3D mapping of the human skeletal muscle mitochondrial network
  Vincent AE,  White K,  Davey T, Philips J, Ogden RT,  Lawess C,  Warren C,  Hall MG,  Ng YS,  Falkous G,  Holden T, Deehan D, Taylor RW,  Turnbull DM,  Picard M.  Cell Rep 2019; 26(4):996-1009    PubMed   PDF

2018

• Sub-cellular origin of mtDNA deletions in human skeletal muscle
  Vincent AE, Rosa HS, Pabis K, Lawless C, Grünewald A, Chen C, Rygiel KA, Rocha MC, Falkous G, Perissi V, White K, Davey T, Grady JP, Petrof B, Sayer AA, Cooper C, Taylor RW, Turnbull DM, Picard M.  Annals Neurol 2018; 84(2):289-301    PubMed   PDF​
• Mitochondrial dynamics in adaptive and maladaptive cellular stress responses
  Eisner V, Picard M, Hajnoczky G. Nat Cell Biol 2018; 20(7):655-665   PubMed   PDF​
  
  
• A mitochondrial health index sensitive to mood and caregiver stress
  Picard M, Prather AA, Puterman E, Cuillerier A, Coccia M, Aschbacher K, Burelle Y, Epel ES. Biol Psychiatr 2018; 84(1):9-17   ​PubMed   PDF​
  
  
• Psychological stress and mitochondria: A systematic review (Part I)
  Picard M, McEwen BS. Psychosom Med 2018; 80(2):141-153   PubMed   PDF
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• Psychological stress and mitochondria: A conceptual framework (Part II)
  Picard M, McEwen BS. Psychosom Med 2018; 80(2):126-140   PubMed   PDF
• An energetic view of stress: Focus on mitochondria
  Picard M, McEwen BS, Epel ES, Sandi C. Front Neuroendocrinol2018; 49:72-85 PubMed   PDF​
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2017

• Mitochondrial nanotunnels
  Vincent AE, Turnbull DM, Hajnoczky G, Eisner V, Picard M. Trends Cell Biol 2017; 27(11):787-799   PubMed   PDF   Suppl
  
  
• Independent impacts of aging on mitochondrial DNA quantity and quality in humans
  Zhang R, Wang Y, Ye K, Picard M, Gu Z.  BMC Genomics 2017; 18:890   PubMed
  
  
• Mitochondrial nexus to allostatic load biomarkers
  Picard M, Juster RP, Sloan RP, McEwen BS. Psychosom Med 2017; 79(1):114-117   PubMed   PD

2016

• The rise of mitochondria in medicine
  ​Picard M, Wallace DC, Burelle Y. Mitochondrion 2016; 30:105-16   PubMed   PDF
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• The spectrum of mitochondrial ultrastructural defects in mitochondrial myopathy
  Vincent AE, Ng YS, White K, Davey T, Mannella C, Falkous G, Feeney C, Schaefer AM, McFarland R, Gorman GS, Taylor RW, 
  Turnbull DM, Picard M. Sci Rep 2016; 6:30610    PubMed   PDF   Suppl
  
  
• Genetic evidence for elevated pathogenicity of mitochondrial DNA heteroplasmy in autism spectrum disorder
  Wang Y, Picard M, Gu Z. Plos Genet 2016; 12(10):e1006391    PubMed   PDF
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• Allostatic load and comorbidities: A mitochondrial, neuroepigenetic, and psychoevolutionary perspective
  Juster RP, Russell JJ, Almeidac D, Picard M. Dev Psychopathol 2016; 28(4pt1):1117:46   PubMed   PDF
  
  
• Disentangling (epi)genetic and environmental contributions to the m.3243A>G MELAS mutation phenotype: Phenotypic destiny in mitochondrial disease?
  Picard M, Hirano M. JAMA Neurol 2016; 73(8):923-5   PubMed   PD

​2015

• Mitochondrial functions modulate neuroendocrine, metabolic, inflammatory and transcriptional responses to psychological stress
  Picard M, McManus MJ, Gray J, Nasca C, Moffat C, Kopinsky P, Seifert E, McEwen BS, Wallace DC. PNAS 2015; 112(48):E6614-23  PubMed   PDF
  
  
• Mitochondrial synapses: Intracellular communication and signal integration
  Picard M. Trends Neurosci 2015; 38(8):468-474   PubMed   PDF
  
  
• Inter-mitochondrial coordination of cristae at regulated membrane junctions
  Picard M, McManus MJ, Csordas G, Varnai P, Dorn GW, Williams D, Hajnoczky G, Wallace DC. Nat Commun 2015; 6:6259  
  ​PubMed   PDF
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• Mitochondrial signaling in neurodegeneration 
  Picard M, McManus MJ. In Reeve AK, Simcox A, Duchen MR, Turnbull DM. (Eds.) Mitochondrial dysfunction in neurodegenerative disorders, 2nd edition, London: Springer (2016)   Link
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2014

• Mitochondrial allostatic load puts the ‘gluc’ back into glucocorticoids
  Picard M, Juster RP, McEwen BS. Nat Rev Endocrinol 2014; 10(5):303-10   PubMed   PDF
  
  
• Progressive increase in mtDNA 3243A>G heteroplasmy results in abrupt transcriptional remodeling
  Picard M, Zhang J, Hanecock S, Derbeneva O, Golhar R, Golik P, O’Hearn S, Levy SE, Potluri P, Lvova M, Davila A, Lin CS, Perin JC, Rappaport EF, Hakonarson H, Trounce I, Procaccio V, Wallace DC. PNAS 2014; 111(38):E4033;4042   PubMed   PDF
  
  
• Mitochondria impact brain function and cognition
  Picard M and McEwen BS. PNAS 2014; 111(1):7-8 [Commentary]   PubMed   PDF
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2013

• Allostatic load as a tool for monitoring comorbidities in schizophrenia and bipolar disorder
  Bizik G, Picard M, Nijjer R, Tourjman V, McEwen BS, Lupien SJ, Juster RP. Harv Rev Neurosci 2013; 21(6):296-313   PubMed   PDF
  
  
• Linking metabolic state and mitochondrial DNA in chronic disease, health and aging
  Picard M, Turnbull DM. Diabetes 2013; 62(3):672-8   PubMed   PDF
  
  
• Mitochondrial morphology transitions and functions: Implications for retrograde signaling?
  Picard M, Shirihai O, Gentil BJ, Burelle Y. Am J Physiol Regul Integr Comp Physiol 2013; 304:R393-406   PubMed   PD

2012 and earlier

• Mitochondria: Starving to reach quorum?
  Picard M and Burelle Y. Bioessays 2012; 43(4):272-4   PubMed   PDF
  
  
• Pathways to aging: The mitochondrion at the intersection of biological and psychosocial sciences
  Picard M. J Aging Res 2011; 814096:1-11   PubMed   PDF
  
  
• Mitochondria: Isolation, structure and function
  Picard M, Taivassalo T, Gouspillou G, Hepple RT. J Physiol (London) 2011; 589(18):4413-21   PubMed   PDF
  
  
• A transdisciplinary perspective of chronic stress in relation to psychopathology throughout lifespan development
  Juster RP, Bizik G, Picard M, Arsenault-Lapierre G, Sindi S, Trepanier L, Marin MF, Wan N, Sekerovic Z, Lord C, Fiocco A, Plusquellec P, McEwen B, Lupien S. Dev Psychopathol 2011; 23(03):725-76    PubMed   PDF
  
  
• Mitochondrial structure and function are disrupted by standard isolation methods
  Picard M, Taivassalo T, Ritchie D, Wright KJ, Thomas MM, Romestaing C, Hepple RT. PLoS One 2011; 6(3):e18317   PubMed    PDF
  
  
• The need for a transdisciplinary, global health framework
  Picard M, Sabiston C, McNamara JK. J Alt Complement Med 2011; 17(2):179-84   PubMed   PDF​
  
  

Complete list of publications

Updated: June  2021