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PREPRINTS
2025
2020
2019
2018 and earlier
- Immune mitochondrial pehonotypes are largely preserved in mitochondrial diseases and do not reflect disease severity
Liu CC, Kurade M, Monzel AS, Kelly C, Juster RP, Trumpff C, Hirano M, Picard M.
Preprint: https://www.biorxiv.org/content/10.1101/2025.01.18.633635v2 - A Quantitative approach to mapping mitochondrial specialization and plasticity
Monzel AS, Devine J, Kapri D, Enriquez JA, Trumpff C, Picard M.
Preprint: https://www.biorxiv.org/content/10.1101/2025.02.03.635951v2 - Brain-body mitochondrial distribution patterns lack coherence and point to tissue-specific and individualized regulatory mechanisms
Devine J, Monzel AS, Shire D, Rosenberg AM, Junker A, Cohen AA, Picard M.
Preprint: www.biorxiv.org/content/10.1101/2024.09.20.614152v1 - A human brain map of mitochondrial respiratory capacity and diversity
Mosharov EV, Rosenberg AM, Monzel AS, Osto CA, Stiles L, Rosoklija GB, Dwork AJ, Bindra S, Zhang Y, Fujita M, Mariani MB, Bakalian M, Sulzer D, De Jager PL, Menon V, Shirihai OS, Mann JJ, Underwood M, Boldrini M, Thiebaut de Schotten M, Picard M.
Preprint: www.biorxiv.org/content/10.1101/2024.03.05.583623v
2025
- A human brain map of mitochondrial respiratory capacity and diversity
Mosharov EV, Rosenberg AM, Monzel AS, Osto CA, Stiles L, Rosoklija GB, Dwork AJ, Bindra S, Junker A, Zhang Y, Fujita M, Mariani MB, Bakalian M, Sulzer D, De Jager PL, Menon V, Shirihai OS, Mann JJ, Underwood M, Boldrini M, Thiebaut de Schotten M, Picard M. Nature 2025 Link PDF Briefing
- Somatic nuclear mitochondrial DNA insertions are prevalent in the human brain and accumulate in aging fibroblasts
Zhou W, Karan KR, Klein H, Sturm G, De Jager P, Bennett D, Hirano M, Picard M, Mills R. PLoS Biol 2024 Link PDF - Psychosocial experiences are associated with human brain mitochondrial biology
Trumpff, C, Monzel A, Sandi C, Menon V, Klein H-U, Fujita M, Lee A, Petyuk VA, Hurst C, Duong DM, Seyfried NT, Wingo AP, Wingo TS, Wang Y, Thambisetty M, Ferrucci L, Bennett DA, De Jager PL, Picard M. PNAS 2024 Link PDF
- Mitochondrial diversity and network organization predict anxiety-like behavior in mice.
Rosenberg A, Saggar M, Monzel AS, Devine J, Rogu P, Mosharov EV, Junker A, Sandi C, Dumitriu D, Anacker C, Picard M. Nat Commun 2023 Link PDF - Multifaceted mitochondria: Moving mitochondrial science beyond function and dysfunction
Monzel AS, Enriques JA, Picard M. Nat Metab 2023 Link PDF
- Mitochondrial signal transduction
Picard M, Shirihai OS. Cell Metabolism 2022 Link PDF - Human studies of mitochondrial biology demonstrate an overall lack of binary sex differences: A multivariate meta-analysis
Junker A, Wang J, Gouspillou G, Ehinger JK, Elmér E, Sjövall F, Fisher-Wellman K, Neufer PD, Molina AJA, Ferrucci L, Picard M.
FASEB J 2022 Link PDF
- Mitochondrial phenotypes in purified human immune cell subtypes and cell mixtures
Rausser S, Trumpff C, McGill MA, Junker A, Wang W, Ho S, Mitchell A, Karan K, Monk C, Segerstrom S, Reed R, Picard M.
eLife 2021 PubMed PDF - Mitochondrial DNA quantity and quality in the human aged and Alzheimer’s disease brain.
Klein H, Trumpff C, Yang HS, Lee AJ, Picard M, Bennett DA, De Jager. Mol Neurodegener 2021 PubMed PDF - Mitochondria in epithelial ovarian carcinoma exhibit abnormal phenotypes and blunted associations with biobehavioral factors
Bindra S, McGill MA, Triplett MK, Tyagi A, Thaker PH, Dahmoush L, Goodheart MJ, Ogden RT, E Owusu-Ansah, Karan KR, Cole S, Sood AK, Lutgendorf SK, Picard M. Sci Rep 2021 PubMed PDF
2020
- Mitochondrial respiratory chain function modulates LPS-induced inflammatory signatures in human blood
Karan KR, Trumpff C, McGill MA, Thomas JE, Sturm G, Lauriola V, Sloan RP, Rohleder N, Kaufman BK, Marsland AL, Picard M.
Brain Behav Immun-Health 2020 PubMed PDF Suppl
2019
- Quantitative 3D mapping of the human skeletal muscle mitochondrial network
Vincent AE, White K, Davey T, Philips J, Ogden RT, Lawess C, Warren C, Hall MG, Ng YS, Falkous G, Holden T, Deehan D, Taylor RW, Turnbull DM, Picard M. Cell Rep 2019 PubMed PDF
2018 and earlier
- Sub-cellular origin of mtDNA deletions in human skeletal muscle
Vincent AE, Rosa HS, Pabis K, Lawless C, Grünewald A, Chen C, Rygiel KA, Rocha MC, Falkous G, Perissi V, White K, Davey T, Grady JP, Petrof B, Sayer AA, Cooper C, Taylor RW, Turnbull DM, Picard M. Annals Neurol 2018 PubMed PDF
- Mitochondrial dynamics in adaptive and maladaptive cellular stress responses
Eisner V, Picard M, Hajnoczky G. Nat Cell Biol 2018 PubMed PDF - Mitochondrial nanotunnels
Vincent AE, Turnbull DM, Hajnoczky G, Eisner V, Picard M. Trends Cell Biol 2017 PubMed PDF Supp
- The spectrum of mitochondrial ultrastructural defects in mitochondrial myopathy
Vincent AE, Ng YS, White K, Davey T, Mannella C, Falkous G, Feeney C, Schaefer AM, McFarland R, Gorman GS, Taylor RW,
Turnbull DM, Picard M. Sci Rep 2016 PubMed PDF Suppl - Genetic evidence for elevated pathogenicity of mitochondrial DNA heteroplasmy in autism spectrum disorder
Wang Y, Picard M, Gu Z. Plos Genet 2016 PubMed PDF
- Allostatic load and comorbidities: A mitochondrial, neuroepigenetic, and psychoevolutionary perspective
Juster RP, Russell JJ, Almeidac D, Picard M. Dev Psychopathol 2016 PubMed PD
- Mitochondrial synapses: Intracellular communication and signal integration
Picard M. Trends Neurosci 2015 PubMed PDF - Inter-mitochondrial coordination of cristae at regulated membrane junctions
Picard M, McManus MJ, Csordas G, Varnai P, Dorn GW, Williams D, Hajnoczky G, Wallace DC. Nat Commun 2015 PubMed PDF
- Mitochondrial signaling in neurodegeneration
Picard M, McManus MJ. In Reeve AK, Simcox A, Duchen MR, Turnbull DM. (Eds.) Mitochondrial dysfunction in neurodegenerative disorders, 2nd edition, London: Springer (2016) Link
- Mitochondrial morphology transitions and functions: Implications for retrograde signaling?
Picard M, Shirihai O, Gentil BJ, Burelle Y. Am J Physiol Regul Integr Comp Physiol 2013 PubMed PDF
- Mitochondria: Starving to reach quorum?
Picard M and Burelle Y. Bioessays 2012 PubMed PDF - Mitochondria: Isolation, structure and function
Picard M, Taivassalo T, Gouspillou G, Hepple RT. J Physiol (London) 2011 PubMed PDF
- Mitochondrial structure and function are disrupted by standard isolation methods
Picard M, Taivassalo T, Ritchie D, Wright KJ, Thomas MM, Romestaing C, Hepple RT. PLoS One 2011 PubMed PDF
