PREPRINTS​

• Context-specific hypermetabolism in humans with mitochondrial energy transformation defects
  Shaulson ED, Sercel AJ, Rausser S, Leonard S, Whyte K, Zuraikat F, Seid H, Huang Q, Junker A, Kapri D, Kurade M, Shire D, Chen J, Trumpff C, Kelly C, Bobba-Alves N, Englestad K, Pontzer H, Shen W, Creasy SA, Melanson EL, Rosenbaum M, St-Onge M, Gallagher D, Hirano M, Picard M.
  Preprint: https://www.medrxiv.org/content/10.64898/2026.05.30.26354528v1.article-info​​
  
  
• Lifetime adversity exposure, mood symptoms, and immune mitochondrial bioenergetics
  Liu CC, Kelly C, Monzel AS, Bekhbat M, Bobba-Alves N, Ramirez V, Slavich GM, Juster RP, Cole SW, Picard M, Trumpff C.
  Preprint: https://www.medrxiv.org/content/10.64898/2026.06.02.26354718v1​
  
  
• Saliva cell-free mitochondrial DNA (cf-mtDNA) as a dynamic biomarker of stress and emotion in daily life; Evidence from two independent repeated-measures studies
  Petri LE, Lee SA, Shire D, Leonard S, Behnke A, Greaney J, Alexander L, Almeida DM, Picard M, Trumpff C.
  Preprint: https://www.medrxiv.org/content/10.64898/2026.03.23.26348537v1
  
  
• Mitochondrial energy transformation capacity influences brain activation during sensory, affective, and cognitive tasks
  Bo K, Kelly C, Trumpff C, Hirano M, de Schotten MT, Picard M, Wagner TD.
  Preprint: https://www.biorxiv.org/content/10.1101/2025.06.25.661482v1
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• Diurnal dynamics and psychobiological regulation of cell-qwqqfree mitochondrial and nuclear DNA in human saliva
  Behnke A, Shire D, Leonard S, Park A, Petri L, Goyal A, Kirschbaum C, Picard M, Trumpff C.
  Preprint: https://www.medrxiv.org/content/10.1101/2025.10.13.25337887v1​
  
  
• Blood mitochondrial health markers cf-mtDNA and GDF15 in human aging
  Trumpff C, Huang Q, Liu CC, Habeck C, Stern Y, Belsky DW, Picard M. 
  Preprint: https://www.biorxiv.org/content/10.1101/2025.01.28.635306v1​
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• A quantitative approach to mapping mitochondrial specialization and plasticity
  Monzel AS, Devine J, Kapri D, Enriquez JA, Trumpff C, Picard M. 
  Preprint: https://www.biorxiv.org/content/10.1101/2025.02.03.635951v3​
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• The energetic stress cytokine GDF15 is induced by chronic and acute psychosocial stress
  Huang Q, Monzel AS, Rausser S, Haahr R, Devine J, Liu CC, Kelly C, Thompson E, Kurade M, Michelson J, Shaulson ED, Li S, Engelstad K, Tanji K, Lauriola V, Wang T, Wang S, Zuraikat FM, St-Onge MP, Kaufman BA, Sloan R, Juster RP, Marsland AL, Gouspillou G, Hirano M, Picard M, Belsky D., Trumpff C. 
  Preprint:  www.biorxiv.org/content/10.1101/2024.04.19.590241v5
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• Accelerated physiology and increased energy expenditure in animals and humans with mitochondrial defects: A meta-analysis
  Sercel A, Sturm G, Shaulson ED, Gallagher D, St-Onge MP, Kempes C, Pontzer H, Hirano M,  Picard M. 
  Preprint: https://www.biorxiv.org/content/10.1101/2023.09.09.556754v1​
  
  
• Accelerating the clock: Interconnected speedup of energetic and molecular dynamics during aging in cultured human cells
  Sturm G,  Bobba-Alves N,  Tumasian III RA, Michelson J,  Ferrucci L, Kempes CP,  Picard M. 
  Preprint: https://www.biorxiv.org/content/10.1101/2022.05.10.491392v4​​